Publications

Johnson RI, Boczkowska B, Alfson K, Weary T, Menzie H, Delgado J, Rodriguez G, Carrion R Jr, Griffiths A. Identification and Characterization of Defective Viral Genomes in Ebola Virus-Infected Rhesus Macaques. J Virol. 2021 Aug 10;95(17):e0071421. doi: 10.1128/JVI.00714-21. Epub 2021 Aug 10. PubMed PMID: 34160256; PubMed Central PMCID: PMC8354239.

Copin R, Baum A, Wloga E, Pascal KE, Giordano S, Fulton BO, Zhou A, Negron N, Lanza K, Chan N, Coppola A, Chiu J, Ni M, Wei Y, Atwal GS, Hernandez AR, Saotome K, Zhou Y, Franklin MC, Hooper AT, McCarthy S, Hamon S, Hamilton JD, Staples HM, Alfson K, Carrion R Jr, Ali S, Norton T, Somersan-Karakaya S, Sivapalasingam S, Herman GA, Weinreich DM, Lipsich L, Stahl N, Murphy AJ, Yancopoulos GD, Kyratsous CA. The monoclonal antibody combination REGEN-COV protects against SARS-CoV-2 mutational escape in preclinical and human studies. Cell. 2021 Jul 22;184(15):3949-3961.e11. doi: 10.1016/j.cell.2021.06.002. Epub 2021 Jun 5. PubMed PMID: 34161776; PubMed Central PMCID: PMC8179113.

Stambaugh A, Stott MA, Meena GG, Tamhankar M, Carrion R Jr, Patterson JL, Hawkins AR, Schmidt H. Optofluidic Amplification-free Multiplex Detection of Viral Hemorrhagic Fevers. IEEE J Sel Top Quantum Electron. 2021 Jul-Aug;27(4). doi: 10.1109/jstqe.2020.3024239. Epub 2020 Sep 16. PubMed PMID: 33390686; PubMed Central PMCID: PMC7774596.

McMahon CL, Staples H, Gazi M, Carrion R, Hsieh J. SARS-CoV-2 targets glial cells in human cortical organoids. Stem Cell Reports. 2021 May 11;16(5):1156-1164. doi: 10.1016/j.stemcr.2021.01.016. PubMed PMID: 33979600; PubMed Central PMCID: PMC8111796.

Vogel AB, Kanevsky I, Che Y, Swanson KA, Muik A, Vormehr M, Kranz LM, Walzer KC, Hein S, Güler A, Loschko J, Maddur MS, Ota-Setlik A, Tompkins K, Cole J, Lui BG, Ziegenhals T, Plaschke A, Eisel D, Dany SC, Fesser S, Erbar S, Bates F, Schneider D, Jesionek B, Sänger B, Wallisch AK, Feuchter Y, Junginger H, Krumm SA, Heinen AP, Adams-Quack P, Schlereth J, Schille S, Kröner C, de la Caridad Güimil Garcia R, Hiller T, Fischer L, Sellers RS, Choudhary S, Gonzalez O, Vascotto F, Gutman MR, Fontenot JA, Hall-Ursone S, Brasky K, Griffor MC, Han S, Su AAH, Lees JA, Nedoma NL, Mashalidis EH, Sahasrabudhe PV, Tan CY, Pavliakova D, Singh G, Fontes-Garfias C, Pride M, Scully IL, Ciolino T, Obregon J, Gazi M, Carrion R Jr, Alfson KJ, Kalina WV, Kaushal D, Shi PY, Klamp T, Rosenbaum C, Kuhn AN, Türeci Ö, Dormitzer PR, Jansen KU, Sahin U. BNT162b vaccines protect rhesus macaques from SARS-CoV-2. Nature. 2021 Apr;592(7853):283-289. doi: 10.1038/s41586-021-03275-y. Epub 2021 Feb 1. PubMed PMID: 33524990.

Rosa BA, Ahmed M, Singh DK, Choreño-Parra JA, Cole J, Jiménez-Álvarez LA, Rodríguez-Reyna TS, Singh B, Gonzalez O, Carrion R Jr, Schlesinger LS, Martin J, Zúñiga J, Mitreva M, Kaushal D, Khader SA. IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection. Commun Biol. 2021 Mar 5;4(1):290. doi: 10.1038/s42003-021-01829-4. PubMed PMID: 33674719; PubMed Central PMCID: PMC7935909.

Alfson KJ, Goez-Gazi Y, Gazi M, Staples H, Mattix M, Ticer A, Klaffke B, Stanfield K, Escareno P, Keiser P, Griffiths A, Chou YL, Niemuth N, Meister GT, Cirimotich CM, Carrion R Jr. Development of a Well-Characterized Rhesus Macaque Model of Ebola Virus Disease for Support of Product Development. Microorganisms. 2021 Feb 26;9(3). doi: 10.3390/microorganisms9030489. PubMed PMID: 33652589; PubMed Central PMCID: PMC7996724.

Simmons SE, Carrion R, Alfson KJ, Staples HM, Jinadatha C, Jarvis WR, Sampathkumar P, Chemaly RF, Khawaja F, Povroznik M, Jackson S, Kaye KS, Rodriguez RM, Stibich MA. Deactivation of SARS-CoV-2 with pulsed-xenon ultraviolet light: Implications for environmental COVID-19 control. Infect Control Hosp Epidemiol. 2021 Feb;42(2):127-130. doi: 10.1017/ice.2020.399. Epub 2020 Aug 3. PubMed PMID: 32741425; PubMed Central PMCID: PMC7443558.

Keiser PT, Anantpadma M, Staples H, Carrion R, Davey RA. Automation of Infectious Focus Assay for Determination of Filovirus Titers and Direct Comparison to Plaque and TCID₅₀ Assays. Microorganisms. 2021 Jan 12;9(1). doi: 10.3390/microorganisms9010156. PubMed PMID: 33445537; PubMed Central PMCID: PMC7826780.

Singh DK, Singh B, Ganatra SR, Gazi M, Cole J, Thippeshappa R, Alfson KJ, Clemmons E, Gonzalez O, Escobedo R, Lee TH, Chatterjee A, Goez-Gazi Y, Sharan R, Gough M, Alvarez C, Blakley A, Ferdin J, Bartley C, Staples H, Parodi L, Callery J, Mannino A, Klaffke B, Escareno P, Platt RN 2nd, Hodara V, Scordo J, Gautam S, Vilanova AG, Olmo-Fontanez A, Schami A, Oyejide A, Ajithdoss DK, Copin R, Baum A, Kyratsous C, Alvarez X, Ahmed M, Rosa B, Goodroe A, Dutton J, Hall-Ursone S, Frost PA, Voges AK, Ross CN, Sayers K, Chen C, Hallam C, Khader SA, Mitreva M, Anderson TJC, Martinez-Sobrido L, Patterson JL, Turner J, Torrelles JB, Dick EJ Jr, Brasky K, Schlesinger LS, Giavedoni LD, Carrion R Jr, Kaushal D. Responses to acute infection with SARS-CoV-2 in the lungs of rhesus macaques, baboons and marmosets. Nat Microbiol. 2021 Jan;6(1):73-86. doi: 10.1038/s41564-020-00841-4. Epub 2020 Dec 18. PubMed PMID: 33340034; PubMed Central PMCID: PMC7890948.

Roozendaal R, Hendriks J, van Effelterre T, Spiessens B, Dekking L, Solforosi L, Czapska-Casey D, Bockstal V, Stoop J, Splinter D, Janssen S, Baelen BV, Verbruggen N, Serroyen J, Dekeyster E, Volkmann A, Wollmann Y, Carrion R Jr, Giavedoni LD, Robinson C, Leyssen M, Douoguih M, Luhn K, Pau MG, Sadoff J, Vandebosch A, Schuitemaker H, Zahn R, Callendret B. Nonhuman primate to human immunobridging to infer the protective effect of an Ebola virus vaccine candidate. NPJ Vaccines. 2020 Dec 17;5(1):112. doi: 10.1038/s41541-020-00261-9. PubMed PMID: 33335092; PubMed Central PMCID: PMC7747701.

Oladunni FS, Park JG, Pino PA, Gonzalez O, Akhter A, Allué-Guardia A, Olmo-Fontánez A, Gautam S, Garcia-Vilanova A, Ye C, Chiem K, Headley C, Dwivedi V, Parodi LM, Alfson KJ, Staples HM, Schami A, Garcia JI, Whigham A, Platt RN 2nd, Gazi M, Martinez J, Chuba C, Earley S, Rodriguez OH, Mdaki SD, Kavelish KN, Escalona R, Hallam CRA, Christie C, Patterson JL, Anderson TJC, Carrion R Jr, Dick EJ Jr, Hall-Ursone S, Schlesinger LS, Alvarez X, Kaushal D, Giavedoni LD, Turner J, Martinez-Sobrido L, Torrelles JB. Lethality of SARS-CoV-2 infection in K18 human angiotensin-converting enzyme 2 transgenic mice. Nat Commun. 2020 Nov 30;11(1):6122. doi: 10.1038/s41467-020-19891-7. PubMed PMID: 33257679; PubMed Central PMCID: PMC7705712.

Baum A, Ajithdoss D, Copin R, Zhou A, Lanza K, Negron N, Ni M, Wei Y, Mohammadi K, Musser B, Atwal GS, Oyejide A, Goez-Gazi Y, Dutton J, Clemmons E, Staples HM, Bartley C, Klaffke B, Alfson K, Gazi M, Gonzalez O, Dick E Jr, Carrion R Jr, Pessaint L, Porto M, Cook A, Brown R, Ali V, Greenhouse J, Taylor T, Andersen H, Lewis MG, Stahl N, Murphy AJ, Yancopoulos GD, Kyratsous CA. REGN-COV2 antibodies prevent and treat SARS-CoV-2 infection in rhesus macaques and hamsters. Science. 2020 Nov 27;370(6520):1110-1115. doi: 10.1126/science.abe2402. Epub 2020 Oct 9. PubMed PMID: 33037066; PubMed Central PMCID: PMC7857396.

Johnson DM, Jokinen JD, Wang M, Pfeffer T, Tretyakova I, Carrion R Jr, Griffiths A, Pushko P, Lukashevich IS. Bivalent Junin & Machupo experimental vaccine based on alphavirus RNA replicon vector. Vaccine. 2020 Mar 23;38(14):2949-2959. doi: 10.1016/j.vaccine.2020.02.053. Epub 2020 Feb 25. PubMed PMID: 32111526; PubMed Central PMCID: PMC7112472.

Liu Y, Wen Z, Carrion R Jr, Nunneley J, Staples H, Ticer A, Patterson JL, Compans RW, Ye L, Yang C. Intradermal Immunization of EBOV VLPs in Guinea Pigs Induces Broader Antibody Responses Against GP Than Intramuscular Injection. Front Microbiol. 2020;11:304. doi: 10.3389/fmicb.2020.00304. eCollection 2020. PubMed PMID: 32174901; PubMed Central PMCID: PMC7056717.

Qin P, Park M, Alfson KJ, Tamhankar M, Carrion R, Patterson JL, Griffiths A, He Q, Yildiz A, Mathies R, Du K. Rapid and Fully Microfluidic Ebola Virus Detection with CRISPR-Cas13a. ACS Sens. 2019 Apr 26;4(4):1048-1054. doi: 10.1021/acssensors.9b00239. Epub 2019 Mar 21. PubMed PMID: 30860365.

Liu Y, Ye L, Lin F, Gomaa Y, Flyer D, Carrion R Jr, Patterson JL, Prausnitz MR, Smith G, Glenn G, Wu H, Compans RW, Yang C. Intradermal Vaccination With Adjuvanted Ebola Virus Soluble Glycoprotein Subunit Vaccine by Microneedle Patches Protects Mice Against Lethal Ebola Virus Challenge. J Infect Dis. 2018 Nov 22;218(suppl_5):S545-S552. doi: 10.1093/infdis/jiy267. PubMed PMID: 29893888; PubMed Central PMCID: PMC6249567.

Pascal KE, Dudgeon D, Trefry JC, Anantpadma M, Sakurai Y, Murin CD, Turner HL, Fairhurst J, Torres M, Rafique A, Yan Y, Badithe A, Yu K, Potocky T, Bixler SL, Chance TB, Pratt WD, Rossi FD, Shamblin JD, Wollen SE, Zelko JM, Carrion R Jr, Worwa G, Staples HM, Burakov D, Babb R, Chen G, Martin J, Huang TT, Erlandson K, Willis MS, Armstrong K, Dreier TM, Ward AB, Davey RA, Pitt MLM, Lipsich L, Mason P, Olson W, Stahl N, Kyratsous CA. Development of Clinical-Stage Human Monoclonal Antibodies That Treat Advanced Ebola Virus Disease in Nonhuman Primates. J Infect Dis. 2018 Nov 22;218(suppl_5):S612-S626. doi: 10.1093/infdis/jiy285. PubMed PMID: 29860496; PubMed Central PMCID: PMC6249601.

Alfson KJ, Avena LE, Beadles MW, Worwa G, Amen M, Patterson JL, Carrion R Jr, Griffiths A. Intramuscular Exposure of Macaca fascicularis to Low Doses of Low Passage- or Cell Culture-Adapted Sudan Virus or Ebola Virus. Viruses. 2018 Nov 16;10(11). doi: 10.3390/v10110642. PubMed PMID: 30453499; PubMed Central PMCID: PMC6267154.

Liu Y, Ye L, Lin F, Gomaa Y, Flyer D, Carrion R Jr, Patterson JL, Prausnitz MR, Smith G, Glenn G, Wu H, Compans RW, Yang C. Intradermal immunization by Ebola virus GP subunit vaccines using microneedle patches protects mice against lethal EBOV challenge. Sci Rep. 2018 Jul 25;8(1):11193. doi: 10.1038/s41598-018-29135-w. PubMed PMID: 30046140; PubMed Central PMCID: PMC6060117.

Callendret B, Vellinga J, Wunderlich K, Rodriguez A, Steigerwald R, Dirmeier U, Cheminay C, Volkmann A, Brasel T, Carrion R, Giavedoni LD, Patterson JL, Mire CE, Geisbert TW, Hooper JW, Weijtens M, Hartkoorn-Pasma J, Custers J, Grazia Pau M, Schuitemaker H, Zahn R. A prophylactic multivalent vaccine against different filovirus species is immunogenic and provides protection from lethal infections with Ebolavirus and Marburgvirus species in non-human primates. PLoS One. 2018;13(2):e0192312. doi: 10.1371/journal.pone.0192312. eCollection 2018. PubMed PMID: 29462200; PubMed Central PMCID: PMC5819775.

Alfson KJ, Avena LE, Delgado J, Beadles MW, Patterson JL, Carrion R Jr, Griffiths A. A Single Amino Acid Change in the Marburg Virus Glycoprotein Arises during Serial Cell Culture Passages and Attenuates the Virus in a Macaque Model of Disease. mSphere. 2018 Jan-Feb;3(1). doi: 10.1128/mSphere.00401-17. eCollection 2018 Jan-Feb. PubMed PMID: 29299527; PubMed Central PMCID: PMC5750385.

Du K, Park M, Griffiths A, Carrion R, Patterson J, Schmidt H, Mathies R. Microfluidic System for Detection of Viral RNA in Blood Using a Barcode Fluorescence Reporter and a Photocleavable Capture Probe. Anal Chem. 2017 Nov 21;89(22):12433-12440. doi: 10.1021/acs.analchem.7b03527. Epub 2017 Nov 7. PubMed PMID: 29073356; PubMed Central PMCID: PMC5990416.

Alfson KJ, Avena LE, Worwa G, Carrion R, Griffiths A. Development of a Lethal Intranasal Exposure Model of Ebola Virus in the Cynomolgus Macaque. Viruses. 2017 Oct 29;9(11). doi: 10.3390/v9110319. PubMed PMID: 29109373; PubMed Central PMCID: PMC5707526.

Du K, Cai H, Park M, Wall TA, Stott MA, Alfson KJ, Griffiths A, Carrion R, Patterson JL, Hawkins AR, Schmidt H, Mathies RA. Multiplexed efficient on-chip sample preparation and sensitive amplification-free detection of Ebola virus. Biosens Bioelectron. 2017 May 15;91:489-496. doi: 10.1016/j.bios.2016.12.071. Epub 2017 Jan 3. PubMed PMID: 28073029; PubMed Central PMCID: PMC5323362.

Ro YT, Ticer A, Carrion R Jr, Patterson JL. Rapid detection and quantification of Ebola Zaire virus by one-step real-time quantitative reverse transcription-polymerase chain reaction. Microbiol Immunol. 2017 Apr;61(3-4):130-137. doi: 10.1111/1348-0421.12475. PubMed PMID: 28332721.

Bengtsson KL, Song H, Stertman L, Liu Y, Flyer DC, Massare MJ, Xu RH, Zhou B, Lu H, Kwilas SA, Hahn TJ, Kpamegan E, Hooper J, Carrion R Jr, Glenn G, Smith G. Matrix-M adjuvant enhances antibody, cellular and protective immune responses of a Zaire Ebola/Makona virus glycoprotein (GP) nanoparticle vaccine in mice. Vaccine. 2016 Apr 7;34(16):1927-35. doi: 10.1016/j.vaccine.2016.02.033. Epub 2016 Feb 24. PubMed PMID: 26921779.

Cap AP, Pidcoke HF, Keil SD, Staples HM, Anantpadma M, Carrion R Jr, Davey RA, Frazer-Abel A, Taylor AL, Gonzales R, Patterson JL, Goodrich RP. Treatment of blood with a pathogen reduction technology using ultraviolet light and riboflavin inactivates Ebola virus in vitro. Transfusion. 2016 Mar;56 Suppl 1:S6-15. doi: 10.1111/trf.13393. PubMed PMID: 27001363; PubMed Central PMCID: PMC5943045.

Alfson KJ, Worwa G, Carrion R Jr, Griffiths A. Determination and Therapeutic Exploitation of Ebola Virus Spontaneous Mutation Frequency. J Virol. 2015 Dec 16;90(5):2345-55. doi: 10.1128/JVI.02701-15. PubMed PMID: 26676781; PubMed Central PMCID: PMC4810732.

Alfson KJ, Avena LE, Beadles MW, Menzie H, Patterson JL, Carrion R Jr, Griffiths A. Genetic Changes at the Glycoprotein Editing Site Associated With Serial Passage of Sudan Virus. J Infect Dis. 2015 Oct 1;212 Suppl 2:S295-304. doi: 10.1093/infdis/jiv216. Epub 2015 Apr 28. PubMed PMID: 25920319; PubMed Central PMCID: PMC6283357.

Li W, Ye L, Carrion R Jr, Mohan GS, Nunneley J, Staples H, Ticer A, Patterson JL, Compans RW, Yang C. Characterization of Immune Responses Induced by Ebola Virus Glycoprotein (GP) and Truncated GP Isoform DNA Vaccines and Protection Against Lethal Ebola Virus Challenge in Mice. J Infect Dis. 2015 Oct 1;212 Suppl 2:S398-403. doi: 10.1093/infdis/jiv186. Epub 2015 Apr 14. PubMed PMID: 25877553; PubMed Central PMCID: PMC4564543.

Cai H, Parks JW, Wall TA, Stott MA, Stambaugh A, Alfson K, Griffiths A, Mathies RA, Carrion R, Patterson JL, Hawkins AR, Schmidt H. Optofluidic analysis system for amplification-free, direct detection of Ebola infection. Sci Rep. 2015 Sep 25;5:14494. doi: 10.1038/srep14494. PubMed PMID: 26404403; PubMed Central PMCID: PMC4585921.

Alfson KJ, Avena LE, Beadles MW, Staples H, Nunneley JW, Ticer A, Dick EJ Jr, Owston MA, Reed C, Patterson JL, Carrion R Jr, Griffiths A. Particle-to-PFU ratio of Ebola virus influences disease course and survival in cynomolgus macaques. J Virol. 2015 Jul;89(13):6773-81. doi: 10.1128/JVI.00649-15. PubMed PMID: 25903348; PubMed Central PMCID: PMC4468478.

Zhou Y, Vedantham P, Lu K, Agudelo J, Carrion R Jr, Nunneley JW, Barnard D, Pöhlmann S, McKerrow JH, Renslo AR, Simmons G. Protease inhibitors targeting coronavirus and filovirus entry. Antiviral Res. 2015 Apr;116:76-84. doi: 10.1016/j.antiviral.2015.01.011. Epub 2015 Feb 7. PubMed PMID: 25666761; PubMed Central PMCID: PMC4774534.

Parks JW, Olson MA, Kim J, Ozcelik D, Cai H, Carrion R Jr, Patterson JL, Mathies RA, Hawkins AR, Schmidt H. Integration of programmable microfluidics and on-chip fluorescence detection for biosensing applications. Biomicrofluidics. 2014 Sep;8(5):054111. doi: 10.1063/1.4897226. eCollection 2014 Sep. PubMed PMID: 25584111; PubMed Central PMCID: PMC4290670.

Griffiths A, Hayhurst A, Davey R, Shtanko O, Carrion R, Patterson JL. Ebola virus infection. In: Singh SK, Ruzek D, editors. Viral hemorrhagic fevers Boca Raton: CRC Press; 2014. 435-456p.

Zapata JC, Carrion R Jr, Patterson JL, Crasta O, Zhang Y, Mani S, Jett M, Poonia B, Djavani M, White DM, Lukashevich IS, Salvato MS. Transcriptome analysis of human peripheral blood mononuclear cells exposed to Lassa virus and to the attenuated Mopeia/Lassa reassortant 29 (ML29), a vaccine candidate. PLoS Negl Trop Dis. 2013;7(9):e2406. doi: 10.1371/journal.pntd.0002406. eCollection 2013. PubMed PMID: 24069471; PubMed Central PMCID: PMC3772037.

Yu G, Yagi S, Carrion R Jr, Chen EC, Liu M, Brasky KM, Lanford RE, Kelly KR, Bales KL, Schnurr DP, Canfield DR, Patterson JL, Chiu CY. Experimental cross-species infection of common marmosets by titi monkey adenovirus. PLoS One. 2013;8(7):e68558. doi: 10.1371/journal.pone.0068558. Print 2013. PubMed PMID: 23894316; PubMed Central PMCID: PMC3722195.

Madrid PB, Chopra S, Manger ID, Gilfillan L, Keepers TR, Shurtleff AC, Green CE, Iyer LV, Dilks HH, Davey RA, Kolokoltsov AA, Carrion R Jr, Patterson JL, Bavari S, Panchal RG, Warren TK, Wells JB, Moos WH, Burke RL, Tanga MJ. A systematic screen of FDA-approved drugs for inhibitors of biological threat agents. PLoS One. 2013;8(4):e60579. doi: 10.1371/journal.pone.0060579. Epub 2013 Apr 5. PubMed PMID: 23577127; PubMed Central PMCID: PMC3618516.

Salvador B, Sexton NR, Carrion R Jr, Nunneley J, Patterson JL, Steffen I, Lu K, Muench MO, Lembo D, Simmons G. Filoviruses utilize glycosaminoglycans for their attachment to target cells. J Virol. 2013 Mar;87(6):3295-304. doi: 10.1128/JVI.01621-12. Epub 2013 Jan 9. PubMed PMID: 23302881; PubMed Central PMCID: PMC3592117.

Shurtleff AC, Garza N, Lackemeyer M, Carrion R Jr, Griffiths A, Patterson J, Edwin SS, Bavari S. The impact of regulations, safety considerations and physical limitations on research progress at maximum biocontainment. Viruses. 2012 Dec;4(12):3932-51. doi: 10.3390/v4123932. Review. PubMed PMID: 23342380; PubMed Central PMCID: PMC3528297.

Carrion R Jr, Bredenbeek P, Jiang X, Tretyakova I, Pushko P, Lukashevich IS. Vaccine Platforms to Control Arenaviral Hemorrhagic Fevers. J Vaccines Vaccin. 2012 Nov 20;3(7). doi: 10.4172/2157-7560.1000160. PubMed PMID: 23420494; PubMed Central PMCID: PMC3573532.

Hayes MW, Carrion R Jr, Nunneley J, Medvedev AE, Salvato MS, Lukashevich IS. Pathogenic Old World arenaviruses inhibit TLR2/Mal-dependent proinflammatory cytokines in vitro. J Virol. 2012 Jul;86(13):7216-26. doi: 10.1128/JVI.06508-11. Epub 2012 Apr 24. PubMed PMID: 22532679; PubMed Central PMCID: PMC3416321.

Carrion R Jr, Patterson JL. An animal model that reflects human disease: the common marmoset (Callithrix jacchus). Curr Opin Virol. 2012 Jun;2(3):357-62. doi: 10.1016/j.coviro.2012.02.007. Epub 2012 Mar 14. Review. PubMed PMID: 22709521; PubMed Central PMCID: PMC3378983.

García M, Cooper A, Shi W, Bornmann W, Carrion R, Kalman D, Nabel GJ. Productive replication of Ebola virus is regulated by the c-Abl1 tyrosine kinase. Sci Transl Med. 2012 Feb 29;4(123):123ra24. doi: 10.1126/scitranslmed.3003500. PubMed PMID: 22378924; PubMed Central PMCID: PMC4794994.

Carrion R Jr, Ro Y, Hoosien K, Ticer A, Brasky K, de la Garza M, Mansfield K, Patterson JL. A small nonhuman primate model for filovirus-induced disease. Virology. 2011 Nov 25;420(2):117-24. doi: 10.1016/j.virol.2011.08.022. Epub 2011 Sep 28. PubMed PMID: 21959017; PubMed Central PMCID: PMC3195836.

Carrion R Jr, Patterson JL. Vaccines against viral hemorrhagic fevers: non-human primate models. Hum Vaccin. 2011 Jun;7(6):667-73. doi: 10.4161/hv.7.6.14981. Epub 2011 Jun 1. Review. PubMed PMID: 21445006.

Jiang X, Dalebout TJ, Bredenbeek PJ, Carrion R Jr, Brasky K, Patterson J, Goicochea M, Bryant J, Salvato MS, Lukashevich IS. Yellow fever 17D-vectored vaccines expressing Lassa virus GP1 and GP2 glycoproteins provide protection against fatal disease in guinea pigs. Vaccine. 2011 Feb 1;29(6):1248-57. doi: 10.1016/j.vaccine.2010.11.079. Epub 2010 Dec 8. PubMed PMID: 21145373; PubMed Central PMCID: PMC3297484.

Griffiths A, Carrion R, Miller JA, Sasinowska H, Sasinowski M, Patterson JL. An electronic inventory system designed to aid compliance with the National Select Agents Registry Program. Applied Biosafety. 2011; 16(1):9-18.

Widman DG, Ishikawa T, Giavedoni LD, Hodara VL, Garza Mde L, Montalbo JA, Travassos Da Rosa AP, Tesh RB, Patterson JL, Carrion R Jr, Bourne N, Mason PW. Evaluation of RepliVAX WN, a single-cycle flavivirus vaccine, in a non-human primate model of West Nile virus infection. Am J Trop Med Hyg. 2010 Jun;82(6):1160-7. doi: 10.4269/ajtmh.2010.09-0310. PubMed PMID: 20519618; PubMed Central PMCID: PMC2877429.

Lieberman MM, Nerurkar VR, Luo H, Cropp B, Carrion R Jr, de la Garza M, Coller BA, Clements D, Ogata S, Wong T, Martyak T, Weeks-Levy C. Immunogenicity and protective efficacy of a recombinant subunit West Nile virus vaccine in rhesus monkeys. Clin Vaccine Immunol. 2009 Sep;16(9):1332-7. doi: 10.1128/CVI.00119-09. Epub 2009 Jul 29. PubMed PMID: 19641099; PubMed Central PMCID: PMC2745014.

LeDuc JW, Anderson K, Bloom ME, Carrion R Jr, Feldmann H, Fitch JP, Geisbert JB, Geisbert TW, Holbrook MR, Jahrling PB, Ksiazek TG. Potential impact of a 2-person security rule on BioSafety Level 4 laboratory workers. Emerg Infect Dis. 2009 Jul;15(7):e1. doi: 10.3201/eid1507.081523. PubMed PMID: 19624910; PubMed Central PMCID: PMC5836487.

Sun Y, Carrion R Jr, Ye L, Wen Z, Ro YT, Brasky K, Ticer AE, Schwegler EE, Patterson JL, Compans RW, Yang C. Protection against lethal challenge by Ebola virus-like particles produced in insect cells. Virology. 2009 Jan 5;383(1):12-21. doi: 10.1016/j.virol.2008.09.020. Epub 2008 Nov 4. PubMed PMID: 18986663; PubMed Central PMCID: PMC2657000.

Lukashevich IS, Carrion R Jr, Salvato MS, Mansfield K, Brasky K, Zapata J, Cairo C, Goicochea M, Hoosien GE, Ticer A, Bryant J, Davis H, Hammamieh R, Mayda M, Jett M, Patterson J. Safety, immunogenicity, and efficacy of the ML29 reassortant vaccine for Lassa fever in small non-human primates. Vaccine. 2008 Sep 26;26(41):5246-54. doi: 10.1016/j.vaccine.2008.07.057. Epub 2008 Aug 8. PubMed PMID: 18692539; PubMed Central PMCID: PMC2582173.

Adams AP, Aronson JF, Tardif SD, Patterson JL, Brasky KM, Geiger R, de la Garza M, Carrion R Jr, Weaver SC. Common marmosets (Callithrix jacchus) as a nonhuman primate model to assess the virulence of eastern equine encephalitis virus strains. J Virol. 2008 Sep;82(18):9035-42. doi: 10.1128/JVI.00674-08. Epub 2008 Jul 9. PubMed PMID: 18614636; PubMed Central PMCID: PMC2546911.

Carrion R, Ro YT, Patterson JL. Leishmaniaviruses. In: Mahy B, Van Regenmortel M, editors. Encycopedia of virology: Vol. 3 Oxford, U.K.: Elsevier; 2008. 220-224p.

Sherwood LJ, Osborn LE, Carrion R Jr, Patterson JL, Hayhurst A. Rapid assembly of sensitive antigen-capture assays for Marburg virus, using in vitro selection of llama single-domain antibodies, at biosafety level 4. J Infect Dis. 2007 Nov 15;196 Suppl 2:S213-9. doi: 10.1086/520586. PubMed PMID: 17940952.

Carrion R Jr, Brasky K, Mansfield K, Johnson C, Gonzales M, Ticer A, Lukashevich I, Tardif S, Patterson J. Lassa virus infection in experimentally infected marmosets: liver pathology and immunophenotypic alterations in target tissues. J Virol. 2007 Jun;81(12):6482-90. doi: 10.1128/JVI.02876-06. Epub 2007 Apr 4. PubMed PMID: 17409137; PubMed Central PMCID: PMC1900113.

Carrion R Jr, Patterson JL, Johnson C, Gonzales M, Moreira CR, Ticer A, Brasky K, Hubbard GB, Moshkoff D, Zapata J, Salvato MS, Lukashevich IS. A ML29 reassortant virus protects guinea pigs against a distantly related Nigerian strain of Lassa virus and can provide sterilizing immunity. Vaccine. 2007 May 16;25(20):4093-102. doi: 10.1016/j.vaccine.2007.02.038. Epub 2007 Feb 27. PubMed PMID: 17360080; PubMed Central PMCID: PMC1892204.

Mabry R, Brasky K, Geiger R, Carrion R Jr, Hubbard GB, Leppla S, Patterson JL, Georgiou G, Iverson BL. Detection of anthrax toxin in the serum of animals infected with Bacillus anthracis by using engineered immunoassays. Clin Vaccine Immunol. 2006 Jun;13(6):671-7. doi: 10.1128/CVI.00023-06. PubMed PMID: 16760326; PubMed Central PMCID: PMC1489546.

Bredenbeek PJ, Molenkamp R, Spaan WJ, Deubel V, Marianneau P, Salvato MS, Moshkoff D, Zapata J, Tikhonov I, Patterson J, Carrion R, Ticer A, Brasky K, Lukashevich IS. A recombinant Yellow Fever 17D vaccine expressing Lassa virus glycoproteins. Virology. 2006 Feb 20;345(2):299-304. doi: 10.1016/j.virol.2005.12.001. Epub 2006 Jan 18. PubMed PMID: 16412488; PubMed Central PMCID: PMC1388090.

Mabry R, Rani M, Geiger R, Hubbard GB, Carrion R Jr, Brasky K, Patterson JL, Georgiou G, Iverson BL. Passive protection against anthrax by using a high-affinity antitoxin antibody fragment lacking an Fc region. Infect Immun. 2005 Dec;73(12):8362-8. doi: 10.1128/IAI.73.12.8362-8368.2005. PubMed PMID: 16299334; PubMed Central PMCID: PMC1307075.

Lukashevich IS, Patterson J, Carrion R, Moshkoff D, Ticer A, Zapata J, Brasky K, Geiger R, Hubbard GB, Bryant J, Salvato MS. A live attenuated vaccine for Lassa fever made by reassortment of Lassa and Mopeia viruses. J Virol. 2005 Nov;79(22):13934-42. doi: 10.1128/JVI.79.22.13934-13942.2005. PubMed PMID: 16254329; PubMed Central PMCID: PMC1280243.

Patterson JL, Carrion R Jr. Demand for nonhuman primate resources in the age of biodefense. ILAR J. 2005;46(1):15-22. doi: 10.1093/ilar.46.1.15. Review. PubMed PMID: 15644560; PubMed Central PMCID: PMC7108618.

Ro YT, Kim EJ, Lee HI, Saiz M, Carrion R Jr, Patterson JL. Evidence that the fully assembled capsid of Leishmania RNA virus 1-4 possesses catalytically active endoribonuclease activity. Exp Mol Med. 2004 Apr 30;36(2):145-56. doi: 10.1038/emm.2004.21. PubMed PMID: 15150443.

Carrion R Jr, Ro YT, Patterson JL. Purification, identification, and biochemical characterization of a host-encoded cysteine protease that cleaves a leishmaniavirus gag-pol polyprotein. J Virol. 2003 Oct;77(19):10448-55. doi: 10.1128/jvi.77.19.10448-10455.2003. PubMed PMID: 12970430; PubMed Central PMCID: PMC228495.

Ogg MM, Carrion R Jr, Botelho AC, Mayrink W, Correa-Oliveira R, Patterson JL. Short report: quantification of leishmaniavirus RNA in clinical samples and its possible role in pathogenesis. Am J Trop Med Hyg. 2003 Sep;69(3):309-13. PubMed PMID: 14628949.

Carrion R, Patterson JL. Advances in Leishmaniavirus research. Research Advances in Virology (India). 2002; 2:33-43.

Scheffter SM, Ro YT, Carrion R, Patterson JL. Leishmaniavirus: a current perspective. Current Topics in Virology. 1999; 1:95-103