Determination of dexamethasone dose for cortisol suppression in adult common marmosets (Callithrix jacchus).

Phillips KA, Lopez M, Salmon AB, Ross CN, Abbott DH, Capitanio JP. Determination of dexamethasone dose for cortisol suppression in adult common marmosets (Callithrix jacchus).. Journal of medical primatology. 2022;51(6):407–410. PMID: 35791288

Abstract

We conducted a dose-response study of dexamethasone to investigate an optimal dexamethasone suppression test for common marmosets. Twelve marmosets received 0.1, 0.5, or 1.0 mg/kg dexamethasone. Doses of 0.5 and 1.0 mg/kg both suppressed endogenous cortisol for at least 18 h with greater individual variability in the lower 0.5 mg/kg dose.

Last updated on 04/14/2023
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