Ebrahimi Laboratory

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A cross-disciplinary research lab dedicated to identifying and solving key questions in virus-host interactions, cancer, and evolution using quantitative biology and big data science approaches followed by targeted experimental studies.

Abou Us https://texasbiomedical.theopenscholar.com/ebrahimi-lab/about

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Cancer

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San Antonio Partnership for Precision Therapeutics fuels COVID-19 research.

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The low abundance of CpG in the SARS-CoV-2 genome is not an evolutionarily signature of ZAP

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Recent Publications

Molecular mechanism for regulating APOBEC3G DNA editing function by the non-catalytic domain.
The low abundance of CpG in the SARS-CoV-2 genome is not an evolutionarily signature of ZAP.
A systematic review of long non-coding RNAs with a potential role in breast cancer.
Human APOBEC3 Variations and Viral Infection.
CANCERSIGN: a user-friendly and robust tool for identification and classification of mutational signatures and patterns in cancer genomes.
Epstein-Barr virus BORF2 inhibits cellular APOBEC3B to preserve viral genome integrity.
Mutation Signatures Including APOBEC in Cancer Cell Lines.
Genetic and mechanistic basis for APOBEC3H alternative splicing, retrovirus restriction, and counteraction by HIV-1 protease.
Opossum APOBEC1 is a DNA mutator with retrovirus and retroelement restriction activity.
Correction: HIV-1 competition experiments in humanized mice show that APOBEC3H imposes selective pressure and promotes virus adaptation.
HIV-1 competition experiments in humanized mice show that APOBEC3H imposes selective pressure and promotes virus adaptation.
Source of CpG Depletion in the HIV-1 Genome.
The DNA cytosine deaminase APOBEC3H haplotype I likely contributes to breast and lung cancer mutagenesis.
A method to avoid errors associated with the analysis of hypermutated viral sequences by alignment-based methods.
Gas chromatography with parallel hard and soft ionization mass spectrometry.

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About Our Lab

A cross-disciplinary research lab dedicated to identifying and solving key questions in virus-host interactions, cancer, and evolution using quantitative biology and big data science approaches followed by targeted experimental studies.

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MEET OUR TEAM

Our Team On The Forefront Of Research

A diverse and growing lab working together to solve complex and challenging problems requiring an interdisciplinary approach by contributing their skills in genetics, virology, cancer, evolution, bioinformatics, mathematics, and statistics.