Research Areas
HIV/SIV Reservoirs in Lymphoid Tissues and Source of Viral Rebound upon Antiretroviral Therapy Interruption
Host-Microbe Interactions and Transcriptomics During SIV Infection With or Without Antiretroviral Therapy
Main Technologies and Methods Used
- Primary Cell Culture
- Cell Isolation from Blood and Tissues
- Viral Immunology
- Flow Cytometry and Cell Sorting
- In situ Hybridization, RNAscope
- Immunofluorescence/Immunohistochemistry
- Confocal Microscopy
- In vivo applications of CRISPR and other Gene Editing Technologies
- Nested PCR, Quantitative PCR, qRT-PCR, ddPCR
- Deep Sequencing, and Transcriptomics
Ongoing Research
- Effects of Substance of Abuse on the CNS
- Therapeutic enhancements on ART-Treated SIV-Infected RM
- Reinvigoration of dysfunctional Cytotoxic T-Cells in SIV-Infected RM
- Mitochondrial Function of Cytotoxic T-Cells in SIV-Infected RM
- CRISPR-based Therapy
