Mahesh Mohan, D.V.M., M.S., Ph.D., Professor | Faculty, Host Pathogen Interaction, Southwest National Primate Research Center
The focus of Dr. Mohan’s laboratory is to investigate epigenetic mechanisms, in particular, the role of microRNAs (miRNAs), long noncoding RNAs (lncRNAs) and DNA methylation in the molecular pathogenesis of HIV/SIV infection. Research in his laboratory is funded by three NIH grants, an R01 grant to study the role of epigenetic mechanisms regulating neuroinflammation in HIV infection. A second R01 focused on determining the role of extracellular vesicles in HIV induced gastrointestinal epithelial dysfunction and lymphoid fibrosis. A third R21/R33 will investigate the role of biomolecular condensates on HIV pathogenesis with a special focus on gastrointestinal and neurological dysfunction. Dr. Mohan has a broad background in veterinary medicine, pathology and molecular biology, with specific training and expertise in key research areas pertaining to nonhuman primate immunology.