Overview
Our laboratory first determined that the “slow parasite clearance” observed in Cambodia was determined by parasite genetics. We showed that the genes responsible for slow clearance were increasing in frequency on the Thai-Myanmar border and we were subsequently able locate the genome region responsible for much of this variation. Following the identification of Kelch13 in this genome regions we have documented the dynamics of soft selective sweeps at this locus on the Thailand-Myanmar border.
antimalarial drug artiminisin,
in a San Antonio garden
border
