The double-edged nature of trained immunity.

Wager, Chrissy M Leopold, and Larry S Schlesinger. 2025. “The Double-Edged Nature of Trained Immunity.”. ELife 14.

Abstract

Trained immunity in alveolar macrophages can lead to damaging lung inflammation, confirming the importance of context in this phenomenon.

Last updated on 07/03/2025
PubMed

The double-edged nature of trained immunity.
Human alveolar macrophage response to Mycobacterium tuberculosis: immune characteristics underlying large inter-individual variability.
Advances in host-directed therapy for tuberculosis and HIV coinfection: enhancing immune responses.
Timing matters in macrophage/CD4+ T cell interactions: an agent-based model comparing Mycobacterium tuberculosis host-pathogen interactions between latently infected and naïve individuals.
Bronchoscopy Without Sedation in Healthy Volunteers: A Viable Approach for Research.
Efficacy and Possible Mechanism(s) of Action of Gallium Tetraphenylporphyrin Nanoparticles against HIV-TB Coinfection in an In Vitro Granuloma Structure Model.

Secondary menu