Anderson Lab 

Parasite genetic variation and evolution, with a focus on malaria parasites and schistosomes.  We believe that the central obstacle to parasite control stems from parasite variation and evolution (drug resistance, vaccine escape, immune evasion, host shifts). Better understanding of the evolution of these biomedically important parasite traits can aid in improving control strategies. At the same time, because selection tends to be strong, parasites infecting humans provide excellent systems for understanding rapid evolution in recombining eukaryotes. Furthermore, genetic variation provides useful tools for better understanding parasite transmission.

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BioRxiv papers

  1. Ebel ER, Kim BY, McDew-White M, Egan ES, Anderson TJC, Petrov DA. Antigenic diversity in malaria parasites is maintained on extrachromosomal DNA 2023:2023.02.02.526885. doi: 10.1101/2023.02.02.526885 %J bioRxiv.