Texas Biomedical Research Institute
Huang Lab
We identify metabolite and lipid compounds of natural sources for T cell activation to fight microbial infections and cancers.
Research
Featured Research Areas
Chemical Biology
- Functional Metabolomics and Lipidomics
- Metabolites and Lipids as T cell Antigens and Protein Ligands
Immunology
- Biology of Metabolite Antigen Presentation
- Biology of Un-conventional T cell Responses
Translational Studies
- Unconventional T cells to Fight Tuberculosis and Cancers
- Comparative transcriptomes reveal pro-survival and cytotoxic programs of mucosal-associated invariant T cells upon Bacillus Calmette-Guérin stimulation.
- CD1 lipidomes reveal lipid-binding motifs and size-based antigen-display mechanisms.
- T cell responses in respiratory viral infections and chronic obstructive pulmonary disease.